Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211960 | 0.86 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TP53TSHRTDP1 | |
| SCHEMBL6943999 | 0.83 | ALDH1A1 (0.58) | ALDH1A1CYP3A4TP53TSHRTDP1 | |
| SCHEMBL14764447 | 0.81 | MAPT (0.38) | ALDH1A1CYP3A4TP53PNMTTSHR | |
| SCHEMBL27893642 | 0.80 | CYP1A2 (0.43) | ALDH1A1CYP3A4TP53TSHRHSD17B10 | |
| SCHEMBL11436863 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CYP3A4PNMTTSHRTDP1 | |
| SCHEMBL14217776 | 0.79 | MAOB (0.44) | ALDH1A1CYP3A4TP53PNMTL3MBTL1 | |
| SCHEMBL23146537 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TP53TSHRTDP1 | |
| SCHEMBL5050464 | 0.76 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TP53TSHRTDP1 | |
| SCHEMBL22366691 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TP53TSHRTDP1 | |
| SCHEMBL28207980 | 0.74 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TP53TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709712-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | Blueprint Medicines Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233900-A1 | GSK3A INHIBITORS AND METHODS OF USE THEREOF | BLUEPRINT MEDICINES CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |