Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764338 | 0.82 | PNMT (0.38) | MAPTNPSR1PNMTALDH1A1KDM4E | |
| SCHEMBL31226430 | 0.81 | ALDH1A1 (0.47) | MAPTNPSR1L3MBTL1PNMTTP53 | |
| SCHEMBL14217776 | 0.79 | MAOB (0.44) | L3MBTL1PNMTTP53CYP3A4ALDH1A1 | |
| SCHEMBL14764226 | 0.77 | THRB (0.46) | MAPTL3MBTL1KMT2AKDM4ETDP1 | |
| SCHEMBL31226570 | 0.76 | MAPT (0.48) | MAPTALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL2042318 | 0.74 | ALDH1A1 (0.47) | MAPTNPSR1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL11336303 | 0.72 | L3MBTL1 (0.49) | MAPTL3MBTL1CYP3A4ALDH1A1NQO1 | |
| SCHEMBL6463455 | 0.72 | TAAR1 (0.43) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| Nitrogen SCHEMBL10975955 | 0.71 | MAPT (0.47) | MAPTNPSR1L3MBTL1TP53CYP3A4 | |
| SCHEMBL469001 | 0.69 | L3MBTL1 (0.60) | MAPTNPSR1L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | claimed |
| WO-2013034119-A1 | 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF | Thanares GmbH (DE) | 2013-03-14 | — | — | WO | disclosed |