Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 5/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.32 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228231 | 0.77 | ADK (0.36) | PRMT5WDR77MAPTP2RX3P2RX4 | |
| SCHEMBL13844430 | 0.71 | P2RX3 (0.53) | P2RX3P2RX4P2RX2ENPP1P2RX6 | |
| SCHEMBL31228638 | 0.70 | ADK (0.38) | PRMT5WDR77P2RX3P2RX4P2RX2 | |
| SCHEMBL13844522 | 0.68 | PRMT6 (0.43) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL31725276 | 0.68 | LMNA (0.60) | LMNAP2RX3P2RX4P2RX2ENPP1 | |
| SCHEMBL17800869 | 0.67 | MEN1 (0.52) | PRMT5WDR77LMNAMAPTP2RX3 | |
| SCHEMBL18595742 | 0.67 | MEN1 (0.52) | PRMT5WDR77LMNAP2RX3P2RX4 | |
| SCHEMBL13844473 | 0.67 | PDE4D (0.39) | LMNAMAPTMEN1USP2POLB | |
| SCHEMBL17800843 | 0.67 | MEN1 (0.52) | PRMT5WDR77LMNAP2RX3P2RX4 | |
| SCHEMBL17816515 | 0.67 | MEN1 (0.52) | PRMT5WDR77LMNAMAPTP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | claimed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | claimed |
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |