SCHEMBL31228223

SCHEMBL31228223

C=C1O[C@@H](n2ccc3c(NC(=O)c4ccccc4)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 1/20 0.45
▸ PRMT5 O14744 11/20 0.41
▸ WDR77 Q9BQA1 10/20 0.41
▸ BRD4 O60885 1/20 0.37
▸ METTL3 Q86U44 1/20 0.37
▸ METTL14 Q9HCE5 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23023836 0.79 ADK (0.72) ADKMETTL3METTL14
SCHEMBL24687181 0.79 ADK (0.72) ADKMETTL3METTL14
SCHEMBL31123791 0.79 ADK (0.72) ADKMETTL3METTL14
SCHEMBL29313461 0.78 ADK (0.60) ADKPRMT5WDR77METTL3METTL14
SCHEMBL31228160 0.78 ADK (0.60) ADKPRMT5WDR77METTL3METTL14
SCHEMBL31167393 0.77 ADK (0.60) ADKMETTL3METTL14
SCHEMBL29313467 0.77 ADK (0.53) ADKPRMT5WDR77METTL3METTL14
SCHEMBL25410585 0.77 ADK (0.60) ADKMETTL3METTL14
SCHEMBL31228171 0.76 ADK (0.46) ADKPRMT5WDR77METTL3METTL14
SCHEMBL27103047 0.76 ADK (0.50) ADKPRMT5WDR77METTL3METTL14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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