SCHEMBL31228272

SCHEMBL31228272

COc1ncnc2c1c(F)cn2[C@@H]1O[C@](F)(CO)[C@@H](O)[C@H]1O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PRMT5 O14744 5/20 0.39
▸ WDR77 Q9BQA1 5/20 0.39
▸ ADK P55263 8/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228088 0.86 ADK (0.45) PRMT5WDR77ADK
SCHEMBL31228253 0.84 ADK (0.51) PRMT5WDR77ADK
SCHEMBL31228469 0.83 ADK (0.48) PRMT5WDR77ADK
SCHEMBL31228186 0.80 PRMT5 (0.46) PRMT5WDR77ADK
SCHEMBL25352899 0.78 ADK (0.61) ADK
SCHEMBL23989110 0.78 ADK (0.61) ADK
SCHEMBL23989402 0.78 ADK (0.61) ADK
SCHEMBL23989401 0.77 ADK (0.52) PRMT5ADK
SCHEMBL23989400 0.77 ADK (0.52) PRMT5ADK
SCHEMBL31228133 0.75 ADORA3 (0.36) ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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