SCHEMBL31228469

SCHEMBL31228469

CNc1ncnc2c1c(F)cn2[C@@H]1O[C@](F)(CO)[C@@H](O)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 6/20 0.48
▸ PRMT5 O14744 5/20 0.43
▸ WDR77 Q9BQA1 4/20 0.43
▸ AHCY P23526 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31228253 0.84 ADK (0.51) ADKPRMT5WDR77
SCHEMBL31228272 0.83 PRMT5 (0.39) ADKPRMT5WDR77
SCHEMBL31228133 0.75 ADORA3 (0.36) ADK
SCHEMBL31725296 0.75 PRMT5 (0.47) ADKPRMT5WDR77
SCHEMBL31228180 0.74 ADK (0.50) ADKPRMT5WDR77
SCHEMBL31228437 0.74 ADK (0.50) ADKPRMT5
SCHEMBL31228211 0.72 ADK (0.59) ADKPRMT5WDR77
SCHEMBL31228230 0.72 ADK (0.48) ADKPRMT5WDR77
SCHEMBL31228248 0.72 ADK (0.60) ADKPRMT5WDR77
SCHEMBL31228076 0.70 ADK (0.41) ADKPRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP claimed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO claimed
EP-4705313-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS The Scripps Research Institute (US) 2026-03-11 — — EP disclosed
WO-2024227159-A2 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-31 — — WO disclosed
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