SCHEMBL312283

SCHEMBL312283

CC(=O)c1cc(CCl)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.49
MAOB P27338 5/20 0.49
KLKB1 P03952 1/20 0.48
CTSB P07858 1/20 0.48
MMP9 P14780 1/20 0.48
DNMT1 P26358 1/20 0.48
DNMT3B Q9UBC3 1/20 0.48
DNMT3L Q9UJW3 1/20 0.48
DNMT3A Q9Y6K1 1/20 0.48
LCK P06239 2/20 0.44
HNF4A P41235 1/20 0.43
KAT8 Q9H7Z6 2/20 0.42
HTT P42858 2/20 0.40
MCL1 Q07820 1/20 0.39
EGFR P00533 1/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4108493 0.85 LCK (0.50) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL13302505 0.84 KLKB1 (0.68) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL21035765 0.84 LCK (0.61) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL3289845 0.82 KLKB1 (0.71) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL8568065 0.82 MAOA (0.50) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL925372 0.82 TRPA1 (0.57) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL27831073 0.81 HSP90AB1 (0.49) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL3289857 0.81 KLKB1 (0.42) MAOAMAOBKLKB1CTSBMMP9
SCHEMBL11745338 0.81 CA1 (0.38) MAOAMAOBKMT2AHSD17B10
SCHEMBL21632307 0.81 PLG (0.49) MAOAMAOBKLKB1CTSBMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3749715-B1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING MATRIX POLYMERS LTD (GB) 2022-04-27 EP disclosed
EP-3749715-A1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING Matrix Polymers Limited (GB) 2020-12-16 EP disclosed
WO-2019155213-A1 POLYMER COMPOSITION FOR ROTATIONAL MOULDING MATRIX POLYMERS LIMITED (GB) 2019-08-15 WO disclosed
US-9636021-B2 Flavonoid compounds of low toxicity for biological imaging applications THE UNIVERSITY OF AKRON (US) 2017-05-02 US disclosed
US-9636021-B2 Flavonoid compounds of low toxicity for biological imaging applications THE UNIVERSITY OF AKRON (US) 2017-05-02 US disclosed
US-20150369812-A1 FLAVONOID COMPOUNDS OF LOW TOXICITY FOR BIOLOGICAL IMAGING APPLICATIONS THE UNIVERSITY OF AKRON 2015-12-24 US disclosed
US-20150369812-A1 FLAVONOID COMPOUNDS OF LOW TOXICITY FOR BIOLOGICAL IMAGING APPLICATIONS THE UNIVERSITY OF AKRON 2015-12-24 US disclosed
EP-2314295-B1 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices RESVERLOGIX INC (CA) 2015-01-28 EP disclosed
US-8410109-B2 Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices RESVERLOGIX CORP. (CA) 2013-04-02 US disclosed
US-8242130-B2 Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases RESVERLOGIX CORP. (CA) 2012-08-14 US disclosed
US-4229515-A Polymers for use in dye image-receiving layers of image transfer film units EASTMAN KODAK COMPANY (US) 1980-10-21 US disclosed
US-4220726-A POLYSTYRENE OR COPOLYMER; COMPLEXING YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1980-09-02 US disclosed
US-4215219-A CHELATING AGENTS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 1980-07-29 US disclosed
EP-0009411-A2 Photographic recording material containing polymers which coordinate with metal ions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-04-02 EP disclosed
US-4169089-A PHOTOSTABILIZERS FOR POLYMERS ARGUS CHEMICAL CORPORATION (US) 1979-09-25 US disclosed
US-4154674-A SELECTIVE REMOVAL OF ANIONS OR CATIONS USING ION EXCHANGE RESINS YEDA RESEARCH & DEVELOPMENT CO., LTD. (IL) 1979-05-15 US disclosed
US-4122200-A 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1978-10-24 US disclosed
US-4097582-A 6',2-(2'-Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1978-06-27 US disclosed
US-4085261-A CHELATING AGENT WITH A STYRENE POLYMER BACKBONE YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1978-04-18 US disclosed
US-3932478-A ULTRAVIOLET LIGHT ABSORBERS, FIRE RETARDANTS BUCKMAN LABORATORIES, INC. (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150369812-A1 FLAVONOID COMPOUNDS OF LOW TOXICITY FOR BIOLOGICAL IMAGING APPLICATIONS MYBBP1A, FABP7, FABP3 MAOA 1780/4885MAOB 698/4885KLKB1 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.