Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.71 |
| ▸ | CTSB | P07858 | 1/20 | 0.71 |
| ▸ | MMP9 | P14780 | 1/20 | 0.71 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.71 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.71 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.71 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.71 |
| ▸ | LCK | P06239 | 2/20 | 0.65 |
| ▸ | HNF4A | P41235 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761882 | 0.85 | LCK (0.71) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL27503796 | 0.84 | PPARA (0.56) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL29414416 | 0.83 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL160646 | 0.83 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL10950033 | 0.83 | LCK (0.89) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL312283 | 0.82 | MAOA (0.49) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL15063308 | 0.82 | FOLH1 (0.56) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL4878532 | 0.82 | KLKB1 (0.74) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL31550006 | 0.82 | KLKB1 (0.74) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL30790801 | 0.82 | LCK (0.85) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111112-A | Refining process for intermediate benzsulfamide of blood glucose-reducing drug glibenclamide | TIANJIN PHARMACEUTICAL GROUP GENCOM PHARMACEUTICAL | 2015-12-02 | — | — | CN | claimed |
| CN-113354666-A | Four kinds of D-A' - (Pi-A)2Type polymeric salicylaldehyde Schiff base derivative metal complex and preparation method and application thereof | 湘潭大学 | 2021-09-07 | — | — | CN | disclosed |
| CN-109890821-A | Amino-pyrrolopyrimidine ketone compound and its application method | 艾科尔公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109641844-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-108884044-A | PIPERIDINE DERIVATIVE | 大塚制药株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-105051038-B | Biaryl-propanoic derivatives and its purposes as drug | 赛诺菲 | 2018-08-03 | — | — | CN | disclosed |
| CN-104411312-B | The combination for being used in treatment neurological or dysbolism use including PDE2 the inhibitor such as methyl of 1 aryl 4 [1,2,4] triazole [4,3 A] quinoxaline compounds and PDE10 inhibitor | 詹森药业有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-105209444-B | It can be used as the benzo-fused heterocycle derivative of GPR120 activator | 詹森药业有限公司 | 2017-12-29 | — | — | CN | disclosed |
| CN-105209444-A | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| CN-105111112-A | Refining process for intermediate benzsulfamide of blood glucose-reducing drug glibenclamide | TIANJIN PHARMACEUTICAL GROUP GENCOM PHARMACEUTICAL | 2015-12-02 | — | — | CN | disclosed |
| CN-103857657-A | Heterocyclic derivative and pharmaceutical drug | NIPPON SHINYAKU CO LTD | 2014-06-11 | — | — | CN | disclosed |
| CN-103619846-A | 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline derivatives | JANSSEN PHARMACEUTICA NV | 2014-03-05 | — | — | CN | disclosed |
| US-7727558-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. | 2007-06-21 | — | — | US | disclosed |
| US-7208483-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-12-18 | — | — | US | disclosed |
| EP-1146860-A4 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECH INC (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1146860-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | Emisphere Technologies, Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000040203-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-07-13 | — | — | WO | disclosed |
| US-4702999-A | ANTIFOGGING AGENTS | MITSUBISHI PAPER MILLS, LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | LPXN, PGF, TTPA | KLKB1 1678/4885CTSB 709/4885MMP9 635/4885 |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | LPXN, PGF, TTPA | KLKB1 1678/4885CTSB 709/4885MMP9 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.