SCHEMBL4787174

SCHEMBL4787174

CC=C(C(=O)O)c1ccccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 8/20 0.56
KDM4E B2RXH2 8/20 0.56
ALDH1A1 P00352 5/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
HMGB1 P09429 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
NAPRT Q6XQN6 1/20 0.56
CA14 Q9ULX7 1/20 0.56
TSHR P16473 3/20 0.48
LMNA P02545 3/20 0.48
HSD17B10 Q99714 5/20 0.48
MAPT P10636 4/20 0.48
BCHE P06276 2/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27782677 1.00 HPGD (0.56) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL3122880 0.81 LMNA (0.52) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL3122885 0.81 LMNA (0.52) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL4787172 0.81 LMNA (0.52) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL5172986 0.81 ALDH1A1 (0.61) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL28994292 0.80 AKR1C1 (0.60) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL9464464 0.79 ERCC5 (0.52) HPGDKDM4EALDH1A1SMN1; SMN2TSHR
SCHEMBL2985717 0.79 LMNA (0.58) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL8397874 0.79 HPGD (0.53) HPGDKDM4EALDH1A1SMN1; SMN2CA12
SCHEMBL8397869 0.79 HPGD (0.53) HPGDKDM4EALDH1A1SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473528-A High intensity sweetner 赛诺米克斯公司 2018-08-31 CN disclosed
WO-2008093325-A2 POLYMORPHS OF 3-(E)-2-{2-[6-(2-CYANOPHENOXY) PYRIMIDIN-4-YLOXY]PHENYL}-3-METHOXYACRYLATE MAKHTESHIM CHEMICAL WORKS LTD. (IL) 2008-08-07 WO disclosed
EP-0664798-B1 THIADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES ZENECA LTD (GB) 1999-12-29 EP disclosed
US-5773445-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-06-30 US disclosed
US-5633256-A Certain pyrimidinyloxy-phenyl acrylates, derivatives thereof and their fungicidal use ZENECA LIMITED (GB) 1997-05-27 US disclosed
US-5602076-A INSECTICIDES, NEMATOCIDES ZENECA LIMITED (GB) 1997-02-11 US disclosed
EP-0667865-B1 OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES ZENECA LTD (GB) 1996-12-11 EP disclosed
US-5470819-A Plant growth regulators, insecticides ZENECA LIMITED (GB) 1995-11-28 US disclosed
EP-0667865-A1 OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES. ZENECA LTD (GB) 1995-08-23 EP disclosed
EP-0664798-A1 THIA- AND OXADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES ZENECA LIMITED (GB) 1995-08-02 EP disclosed
US-5438066-A Fungicide, insecticide, miticide and pesticide ZENECA LIMITED (GB) 1995-08-01 US disclosed
WO-1995005368-A1 THIA- AND OXADIAZOLE DERIVATIVES AND THEIR USE AS FUNGICIDES OR INSECTICIDES ZENECA LIMITED (GB) 1995-02-23 WO disclosed
WO-1994010159-A1 OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES ZENECA LIMITED (GB) 1994-05-11 WO disclosed
EP-0242081-B1 Fungicides ZENECA LTD (GB) 1994-04-27 EP disclosed
US-5057146-A CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-15 US disclosed
EP-0391451-A1 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-10 EP disclosed
EP-0387923-A2 Fungicides ZENECA LIMITED (GB) 1990-09-19 EP disclosed
EP-0242081-A1 Fungicides ZENECA LIMITED (GB) 1987-10-21 EP disclosed