Sugi Predict

Sugi Predict / Compounds / SCHEMBL710656

SCHEMBL710656

SCHEMBL710656

CO/C=C(/C(=O)OC)c1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.55
▸ TSHR P16473 2/20 0.55
▸ KDM4E B2RXH2 4/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HIF1A Q16665 2/20 0.43
▸ MPO P05164 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ HPGD P15428 4/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ CA12 O43570 2/20 0.42
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 2/20 0.42
▸ CA7 P43166 2/20 0.42
▸ CA9 Q16790 2/20 0.42
▸ CA14 Q9ULX7 2/20 0.42
▸ HMGB1 P09429 1/20 0.42
▸ CA4 P22748 1/20 0.42
▸ CA6 P23280 1/20 0.42
▸ NAPRT Q6XQN6 1/20 0.42
▸ NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1223756 1.00 LMNA (0.55) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL29721816 1.00 LMNA (0.55) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL1223761 1.00 LMNA (0.55) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL17755553 0.86 LMNA (0.58) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL2985717 0.86 LMNA (0.58) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL4787172 0.84 LMNA (0.52) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL3122885 0.84 LMNA (0.52) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL3122880 0.84 LMNA (0.52) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL7698025 0.83 LMNA (0.47) LMNATSHRKDM4ESMN1; SMN2HIF1A
SCHEMBL7516474 0.83 LMNA (0.47) LMNATSHRKDM4ESMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 — — US disclosed
US-11369113-B2 Vector control compositions, methods and products utilizing same SYNGENTA PARTICIPATIONS AG (CH) 2022-06-28 — — US disclosed
US-20220194903-A1 PROCESS FOR THE PREPARATION OF FUNGICIDALLY ACTIVE STROBILURIN COMPOUNDS AND INTERMEDIATES THEREOF UPL LTD (IN) 2022-06-23 — — US disclosed
CN-114380740-A Synthesis method of polysubstituted pyridine-2-oxygen ether compound 江阴苏利化学股份有限公司 2022-04-22 — — CN disclosed
EP-3700893-B1 VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2021-11-17 — — EP disclosed
WO-2021024135-A1 AN IMPROVED PROCESS FOR PREPARATION OF METHYL (2E)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE COROMANDEL INTERNATIONAL LIMITED (IN) 2021-02-11 — — WO disclosed
WO-2020212928-A1 PROCESS FOR THE PREPARATION OF FUNGICIDALLY ACTIVE STROBILURIN COMPOUNDS AND INTERMEDIATES THEREOF UPL LIMITED (IN) 2020-10-22 — — WO disclosed
US-20200315175-A1 Vector Control Compositions, Methods And Products Utilizing Same SYNGENTA PARTICIPATIONS AG (CH) 2020-10-08 — — US disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 — — US disclosed
EP-3004066-B1 PROCESS FOR PREPARING 4,6-BIS(ARYLOXY)PYRIMIDINE DERIVATIVES CHEMINOVA AS (DK) 2018-04-11 — — EP disclosed
US-5124329-A For plants IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-23 — — US disclosed
EP-0468695-A1 Fungicides ZENECA LIMITED (GB) 1992-01-29 — — EP disclosed
EP-0468684-A2 Propenoic acid derivatives, process for their preparation and their use as fungicides ZENECA LIMITED (GB) 1992-01-29 — — EP disclosed
US-5059605-A Methyl 2-(pyridyloxypyrimidinyleneoxyphenylene)-3-methoxypropenoates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-22 — — US disclosed
US-5057146-A CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-10-15 — — US disclosed
EP-0391451-A1 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-10-10 — — EP disclosed
EP-0387923-A2 Fungicides ZENECA LIMITED (GB) 1990-09-19 — — EP disclosed
EP-0382375-A2 Fungicides ZENECA LIMITED (GB) 1990-08-16 — — EP disclosed
US-4895974-A AGRICULTURE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-01-23 — — US disclosed
EP-0242081-A1 Fungicides ZENECA LIMITED (GB) 1987-10-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 LMNA 2239/4885TSHR 4878/4885KDM4E 324/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 LMNA 2239/4885TSHR 4878/4885KDM4E 324/4885
US-11369113-B2 Vector control compositions, methods and products utilizing same DDT, MSMO1, MGLL LMNA 2076/4885TSHR 4883/4885KDM4E 430/4885
US-20200315175-A1 Vector Control Compositions, Methods And Products Utilizing Same DDT, MSMO1, MGLL LMNA 2076/4885TSHR 4883/4885KDM4E 430/4885
US-20220194903-A1 PROCESS FOR THE PREPARATION OF FUNGICIDALLY ACTIVE STROBILURIN COMPOUNDS AND INTERMEDIATES THEREOF CYP51A1, STS, TYR LMNA 3068/4885TSHR 4346/4885KDM4E 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.