Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244590 | 0.81 | RAB9A (0.51) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL31229651 | 0.79 | KDM4E (0.42) | ALDH1A1GAAPOLBKDM4EHPGD | |
| SCHEMBL31229886 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL31229783 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL31229592 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL10004177 | 0.78 | ALDH1A1 (0.73) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL31229731 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL25242879 | 0.74 | GRIN2D (0.46) | ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL2311400 | 0.74 | GABRA1 (0.56) | ALDH1A1MAPTLMNAL3MBTL1GAA | |
| SCHEMBL31422901 | 0.74 | MAPT (0.55) | ALDH1A1MAPTLMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024222866-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-10-31 | — | — | WO | disclosed |