Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848610 | 0.89 | KDM4E (0.64) | HTR1APOLB | |
| SCHEMBL31232796 | 0.86 | SMN1; SMN2 (0.62) | HTR1ASMN1; SMN2POLBSCN2A | |
| SCHEMBL3026254 | 0.83 | HTR1A (0.83) | HTR1ASMN1; SMN2 | |
| SCHEMBL31232754 | 0.82 | HTR1A (0.80) | HTR1A | |
| SCHEMBL31232816 | 0.81 | ADRA1D (0.71) | HTR1A | |
| SCHEMBL31232843 | 0.81 | ADRA1D (0.71) | HTR1A | |
| SCHEMBL10036171 | 0.81 | HTR1A (0.69) | HTR1A | |
| SCHEMBL12431530 | 0.81 | MAPT (0.70) | HTR1APOLBSIRT6 | |
| SCHEMBL31232849 | 0.80 | DRD2 (0.71) | HTR1ASMN1; SMN2 | |
| SCHEMBL2517968 | 0.79 | HTR1A (0.66) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233922-A2 | PYRIDINE-PIPERAZINE-BASED SCAFFOLDS AS HIGHLY POTENT AND SELECTIVE NEUROLYSIN ACTIVATORS | TEXAS TECH UNIVERSITY SYSTEM (US) | 2024-11-14 | — | — | WO | disclosed |