Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | RAD52 | P43351 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 6/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR6 | P50406 | 6/20 | 0.59 |
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31232867 | 0.89 | HTR1A (0.60) | POLBHTR1A | |
| SCHEMBL11632287 | 0.84 | HTR7 (0.70) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11631848 | 0.83 | KDM4E (0.86) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11630456 | 0.83 | HTR1A (0.71) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11636824 | 0.81 | L3MBTL1 (0.49) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11835734 | 0.81 | KDM4E (0.65) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11631571 | 0.81 | HTR1A (0.85) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL31232796 | 0.79 | SMN1; SMN2 (0.62) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11842208 | 0.79 | KDM4E (0.61) | KDM4ERAD52MEN1POLBKMT2A | |
| SCHEMBL11441512 | 0.79 | MEN1 (0.83) | KDM4ERAD52MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940397-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-02-24 | — | — | US | disclosed |