Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26126648 | 1.00 | CYP2D6 (0.37) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| SCHEMBL26669575 | 0.77 | CYP2D6 (0.49) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| SCHEMBL25259343 | 0.70 | CHRNB2 (0.35) | CHRNA1ESR1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL26124046 | 0.69 | GPR119 (0.45) | — | |
| SCHEMBL26121984 | 0.68 | TSHR (0.42) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| SCHEMBL10188524 | 0.68 | CYP3A4 (0.36) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| SCHEMBL30599902 | 0.68 | TSHR (0.42) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| Trifluoroacetic Acid SCHEMBL26600638 | 0.67 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| Trifluoroacetic Acid SCHEMBL30619105 | 0.67 | CYP2D6 (0.42) | CYP2D6CYP1A2CYP3A4TSHRMEN1 | |
| SCHEMBL31250340 | 0.67 | HTR2A (0.39) | CHRNA1ESR1CHRNGCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119183453-A | STAT modulators and uses thereof | 瑞克鲁迪克斯制药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |