Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 16/20 | 0.68 |
| ▸ | EPAS1 | Q99814 | 16/20 | 0.68 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969426 | 0.80 | HIF1A (0.70) | HIF1AEPAS1 | |
| SCHEMBL30377279 | 0.68 | HIF1A (0.78) | HIF1AEPAS1 | |
| SCHEMBL19261658 | 0.67 | DHODH (0.56) | PTPN1PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL29520661 | 0.66 | HIF1A (1.00) | HIF1AEPAS1 | |
| SCHEMBL29934508 | 0.64 | HIF1A (1.00) | HIF1AEPAS1 | |
| SCHEMBL27489471 | 0.62 | VKORC1 (0.67) | MGAMGAASIPTPN1MGAM2 | |
| SCHEMBL24074938 | 0.62 | PTGES (0.57) | HIF1AEPAS1PTPN1PTGESALOX5 | |
| SCHEMBL19261676 | 0.62 | DHODH (0.54) | PTPN1PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL24075662 | 0.61 | PTGES (0.72) | MGAMPTPN1PTGESALOX5PTGS1 | |
| SCHEMBL31237267 | 0.60 | HIF1A (1.00) | HIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |