Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TTK | P33981 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 7/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 4/20 | 0.44 |
| ▸ | JAK3 | P52333 | 4/20 | 0.44 |
| ▸ | CDK1 | P06493 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.44 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.44 |
| ▸ | MARK3 | P27448 | 3/20 | 0.44 |
| ▸ | TYK2 | P29597 | 3/20 | 0.44 |
| ▸ | CLK2 | P49760 | 3/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240433 | 0.90 | CDK1 (0.51) | TTKJAK2MAPK14WNT3AROCK1 | |
| SCHEMBL31240463 | 0.87 | PSEN1 (0.54) | JAK2MAPK14WNT3AROCK1PLK4 | |
| SCHEMBL31240445 | 0.87 | WNT3A (0.47) | MAPK1TTKJAK2MAPK14WNT3A | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | TTKJAK2MAPK14WNT3ACDK1 | |
| SCHEMBL31240382 | 0.85 | MAPK1 (0.52) | MAPK1MAPK14WNT3AROCK1CDK1 | |
| SCHEMBL31240399 | 0.85 | JAK2 (0.54) | MAPK1JAK2WNT3APLK4CDK1 | |
| SCHEMBL31240402 | 0.85 | ROCK1 (0.54) | WNT3AROCK1CYP3A4CDK2ROCK2 | |
| SCHEMBL31240714 | 0.84 | WNT3A (0.55) | JAK2MAPK14WNT3AROCK1PLK4 | |
| SCHEMBL31240563 | 0.82 | DYRK1A (0.51) | JAK2WNT3ACLK2DYRK1APIK3C3 | |
| SCHEMBL31240509 | 0.82 | JAK2 (0.56) | TTKJAK2MAPK14WNT3ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |