Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 7/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.48 |
| ▸ | JAK3 | P52333 | 4/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.46 |
| ▸ | PLK4 | O00444 | 3/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.46 |
| ▸ | MARK3 | P27448 | 3/20 | 0.46 |
| ▸ | TYK2 | P29597 | 3/20 | 0.46 |
| ▸ | CLK2 | P49760 | 3/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240308 | 0.90 | MAPK1 (0.49) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240714 | 0.88 | WNT3A (0.55) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240675 | 0.88 | WNT3A (0.52) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240349 | 0.86 | WNT3A (0.50) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240240 | 0.86 | MAPK14 (0.55) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240509 | 0.86 | JAK2 (0.56) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240322 | 0.86 | MAPK10 (0.58) | CDK2WNT3AROCK2CDK5ROCK1 | |
| SCHEMBL31240457 | 0.86 | WNT3A (0.50) | CDK1CDK2CDK4JAK2WNT3A | |
| SCHEMBL31240462 | 0.85 | JAK2 (0.54) | CDK1CDK2JAK2MAPK14JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |