Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240445 | 0.90 | WNT3A (0.47) | JAK2CDK1CDK2RIOK2MAPK1 | |
| SCHEMBL31240349 | 0.89 | WNT3A (0.50) | JAK2CDK1CDK4CDK2GSK3A | |
| SCHEMBL31240493 | 0.89 | WNT3A (0.57) | JAK2CDK1CDK4CDK2RIOK2 | |
| SCHEMBL31240382 | 0.89 | MAPK1 (0.52) | CDK1CDK4CDK2MAPK1WNT3A | |
| SCHEMBL31240463 | 0.89 | PSEN1 (0.54) | JAK2CDK1CDK4CDK2GSK3A | |
| SCHEMBL31240538 | 0.86 | DYRK1A (0.52) | RIOK2WNT3AKDRANO1MKNK2 | |
| SCHEMBL31240402 | 0.86 | ROCK1 (0.54) | CDK2GSK3AMAPK10RIOK2WNT3A | |
| SCHEMBL31240563 | 0.85 | DYRK1A (0.51) | JAK2WNT3ACLK2 | |
| SCHEMBL31240509 | 0.85 | JAK2 (0.56) | JAK2CDK1CDK4CDK2WNT3A | |
| SCHEMBL31240675 | 0.85 | WNT3A (0.52) | JAK2CDK1CDK4CDK2RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |