Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.52 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240404 | 0.90 | MAPK14 (0.52) | DYRK1ARIOK2NR3C2CYP2D6PSEN1 | |
| SCHEMBL31240382 | 0.88 | MAPK1 (0.52) | DYRK1ANR3C2ROCK2MKNK1MKNK2 | |
| SCHEMBL31240445 | 0.88 | WNT3A (0.47) | DYRK1ARIOK2KDRPLK4AURKA | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | DYRK1ARIOK2MEN1KMT2AWNT3A | |
| SCHEMBL31240463 | 0.86 | PSEN1 (0.54) | RIOK2NR3C2KDRPLK4AURKA | |
| SCHEMBL31240399 | 0.86 | JAK2 (0.54) | RIOK2KDRPLK4AURKAROCK2 | |
| SCHEMBL31240402 | 0.84 | ROCK1 (0.54) | RIOK2NR3C2ROCK2WNT3A | |
| SCHEMBL31240240 | 0.83 | MAPK14 (0.55) | MEN1KMT2AWNT3A | |
| SCHEMBL31240509 | 0.83 | JAK2 (0.56) | DYRK1AMEN1KMT2AWNT3A | |
| SCHEMBL31240675 | 0.83 | WNT3A (0.52) | RIOK2KDRPLK4AURKAROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |