Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.55 |
| ▸ | WNT3A | P56704 | 5/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240402 | 0.90 | ROCK1 (0.54) | MAPK10RIOK2WNT3AGSK3ACDK2 | |
| SCHEMBL31240436 | 0.90 | WNT3A (0.47) | MAPK10ALDH1A1SMN1; SMN2L3MBTL1RIOK2 | |
| SCHEMBL31240714 | 0.89 | WNT3A (0.55) | MAPK10ALDH1A1SMN1; SMN2L3MBTL1RIOK2 | |
| SCHEMBL31240675 | 0.89 | WNT3A (0.52) | RIOK2WNT3ACDK2CDK5MEN1 | |
| SCHEMBL31240240 | 0.87 | MAPK14 (0.55) | WNT3ACDK2MEN1RAB9AKMT2A | |
| SCHEMBL31240349 | 0.87 | WNT3A (0.50) | MAPK10RIOK2WNT3AGSK3ACDK2 | |
| SCHEMBL31240509 | 0.87 | JAK2 (0.56) | WNT3ACDK2MEN1RAB9AKMT2A | |
| SCHEMBL31240493 | 0.87 | WNT3A (0.57) | RIOK2WNT3ACDK2MEN1RAB9A | |
| SCHEMBL31240457 | 0.86 | WNT3A (0.50) | RIOK2WNT3ACDK2MEN1RAB9A | |
| SCHEMBL31240433 | 0.86 | CDK1 (0.51) | RIOK2WNT3AGSK3ACDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |