Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 5/20 | 0.47 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240276 | 0.90 | ROCK1 (0.43) | WNT3ARIOK2MAPK10JAK2CDK2 | |
| SCHEMBL31240322 | 0.90 | MAPK10 (0.58) | WNT3ARIOK2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL31240675 | 0.88 | WNT3A (0.52) | WNT3ARIOK2MEN1RAB9AKMT2A | |
| SCHEMBL31240240 | 0.86 | MAPK14 (0.55) | WNT3AMEN1RAB9AKMT2AJAK2 | |
| SCHEMBL31240349 | 0.86 | WNT3A (0.50) | WNT3ARIOK2MAPK10MEN1RAB9A | |
| SCHEMBL31240714 | 0.86 | WNT3A (0.55) | WNT3ARIOK2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL31240493 | 0.86 | WNT3A (0.57) | WNT3ARIOK2MEN1RAB9AKMT2A | |
| SCHEMBL31240509 | 0.86 | JAK2 (0.56) | WNT3AMEN1RAB9AKMT2AJAK2 | |
| SCHEMBL31240457 | 0.84 | WNT3A (0.50) | WNT3ARIOK2MEN1RAB9AKMT2A | |
| SCHEMBL31240404 | 0.84 | MAPK14 (0.52) | WNT3ARIOK2JAK2CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |