Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240797 | 0.81 | ALDH1A1 (0.56) | KDRLMNASMN1; SMN2 | |
| SCHEMBL31240483 | 0.79 | MAP4K4 (0.53) | MAP4K4MAPK8EGFRKDRCHUK | |
| SCHEMBL31240792 | 0.79 | CHUK (0.53) | MAPK8CHUKINSRCAMKK2ITK | |
| SCHEMBL31240796 | 0.75 | CHUK (0.42) | MAPK8EGFRCHUKINSRCAMKK2 | |
| SCHEMBL31240646 | 0.75 | CHUK (0.62) | MAPK8CHUKINSRCAMKK2IKBKB | |
| SCHEMBL2444894 | 0.73 | CCNB2 (0.64) | CHUKIKBKBCSF1R | |
| SCHEMBL31240729 | 0.72 | CD74 (0.50) | MAPK8EGFRCHUKINSRCAMKK2 | |
| SCHEMBL31240751 | 0.72 | CCNB2 (0.61) | EGFRCSF1R | |
| SCHEMBL31240620 | 0.72 | PRKCI (0.54) | MAP4K4MAPK8EGFRKDRCHUK | |
| SCHEMBL16041244 | 0.70 | CDC7 (0.59) | EGFRAURKAAURKBCSF1RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |