Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 3/20 | 0.62 |
| ▸ | INSR | P06213 | 2/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.62 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.62 |
| ▸ | KIT | P10721 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240753 | 0.84 | KIT (0.50) | CHUKINSRMAPK8CAMKK2KIT | |
| SCHEMBL31240667 | 0.84 | CDK9 (0.46) | CHUKINSRMAPK8CAMKK2KIT | |
| SCHEMBL31240593 | 0.77 | CDC7 (0.59) | CYP1A2ALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL16041244 | 0.77 | CDC7 (0.59) | CYP1A2ALDH1A1LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL4764919 | 0.77 | BRAF (0.58) | CHUKINSRMAPK8CAMKK2KIT | |
| SCHEMBL31240751 | 0.77 | CCNB2 (0.61) | CDC7PIM1CDK9 | |
| SCHEMBL31240688 | 0.77 | CDK9 (0.50) | CDC7PIM1CDK9MEN1 | |
| SCHEMBL2444894 | 0.76 | CCNB2 (0.64) | CHUKNPY5RIKBKBCLK4CDC7 | |
| SCHEMBL31240562 | 0.76 | CDK9 (0.47) | CDC7PIM1CDK9 | |
| SCHEMBL31240729 | 0.75 | CD74 (0.50) | CHUKINSRMAPK8CAMKK2CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |