Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240646 | 0.84 | CHUK (0.62) | CDK9CDC7PIM1CHUKINSR | |
| SCHEMBL31240727 | 0.80 | DCUN1D1 (0.50) | CDK9CDC7PIM1 | |
| SCHEMBL31240753 | 0.78 | KIT (0.50) | CHUKINSRMAPK8CAMKK2SYK | |
| SCHEMBL31240593 | 0.78 | CDC7 (0.59) | CDK9CDC7PIM1MAPK14EGFR | |
| SCHEMBL16041244 | 0.78 | CDC7 (0.59) | CDK9CDC7PIM1MAPK14EGFR | |
| SCHEMBL31240751 | 0.78 | CCNB2 (0.61) | CDK9CDC7PIM1MAPK14EGFR | |
| SCHEMBL31240688 | 0.78 | CDK9 (0.50) | CDK9CDC7PIM1CCNT1EGFR | |
| SCHEMBL31240562 | 0.77 | CDK9 (0.47) | CDK9CDC7PIM1CCNT1 | |
| SCHEMBL2444894 | 0.77 | CCNB2 (0.64) | CDK9CDC7PIM1CHUKMAPK14 | |
| SCHEMBL4909734 | 0.77 | NR1H2 (0.48) | NR1H2NR1H3SYKKITEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |