SCHEMBL7415340

SCHEMBL7415340

O=C(CCc1cccc(Cl)c1)Nc1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.59
TSHR P16473 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 2/20 0.58
CSNK1D P48730 1/20 0.56
NPC1 O15118 1/20 0.54
MITF O75030 1/20 0.54
TP53 P04637 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
XBP1 P17861 1/20 0.54
RAB9A P51151 1/20 0.54
CNR2 P34972 1/20 0.53
HSP90B1 P14625 1/20 0.53
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC7 Q8WUI4 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776518 0.84 GAA (0.83) GAAALDH1A1LMNATSHRL3MBTL1
SCHEMBL31240652 0.81 LMNA (0.65) GAAALDH1A1LMNATSHRL3MBTL1
SCHEMBL30781999 0.78 NPC1 (0.59) GAATSHRKMT2ANPC1MITF
SCHEMBL6963065 0.77 ALDH1A1 (0.74) GAAALDH1A1LMNAKMT2ANPC1
SCHEMBL24335559 0.77 CACNA1G (0.79) ALDH1A1LMNATSHRL3MBTL1CSNK1D
SCHEMBL9665286 0.74 HDAC3 (0.72) GAAALDH1A1KMT2ANPC1PKM
SCHEMBL27522677 0.74 HCAR2 (0.76) NPC1RAB9AMAPK1ALOX15KDM4E
SCHEMBL13676198 0.74 GAA (0.61) GAAALDH1A1LMNATSHRL3MBTL1
SCHEMBL15672954 0.74 GAA (0.73) GAAALDH1A1KMT2ANPC1PKM
SCHEMBL13149787 0.74 GAA (0.73) GAAALDH1A1KMT2ANPC1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4062848-A ANTIHISTAMINE AKZONA INCORPORATED (US) 1977-12-13 US disclosed