Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.56 |
| ▸ | CDC7 | O00311 | 3/20 | 0.56 |
| ▸ | PIM1 | P11309 | 3/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240676 | 0.82 | CDK9 (0.39) | CDK9CDC7PIM1HRH4HRH3 | |
| SCHEMBL31240703 | 0.81 | TBK1 (0.49) | CCNKCDK12 | |
| SCHEMBL31240691 | 0.80 | CDK9 (0.52) | CDK9CDC7PIM1CDK1CCNT1 | |
| SCHEMBL31240575 | 0.79 | MAP3K11 (0.41) | CDK9CDC7PIM1CDK1CDK2 | |
| SCHEMBL31240380 | 0.79 | CLK2 (0.41) | CDK9CDC7PIM1HRH4HRH3 | |
| SCHEMBL31240799 | 0.77 | CDK9 (0.42) | CDK9CDC7PIM1CDK1CDK2 | |
| SCHEMBL31240636 | 0.75 | CDK9 (0.40) | CDK9CDC7PIM1CCNT1 | |
| SCHEMBL31240929 | 0.74 | CDK9 (0.49) | CDK9CDC7PIM1CDK1CDK2 | |
| SCHEMBL31240785 | 0.74 | CDK9 (0.47) | CDK9CDC7PIM1CDK1CCNT1 | |
| SCHEMBL31240630 | 0.72 | CDC7 (0.52) | CDK9CDC7PIM1CDK1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |