Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL6938284 | 0.95 | MGLL (0.68) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL7121916 | 0.83 | SMN1; SMN2 (0.77) | GAASMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL10723816 | 0.83 | RAB9A (0.80) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL4171372 | 0.80 | KMT2A (0.73) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL28916553 | 0.79 | MGLL (0.64) | MGLLKDM4ERAB9AGAASMN1; SMN2 | |
| SCHEMBL3456393 | 0.78 | KMT2A (0.72) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL3454984 | 0.78 | KMT2A (0.72) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL29944094 | 0.78 | KMT2A (0.72) | MGLLKDM4ERXFP1RAB9AGAA | |
| SCHEMBL19357183 | 0.77 | MGLL (0.69) | MGLLKDM4EALDH1A1KMT2A | |
| SCHEMBL554704 | 0.77 | MGLL (0.67) | MGLLRAB9AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964834-A1 | Sulphonyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |