Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.59 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.59 |
| ▸ | ITGAV | P06756 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | PPID | Q08752 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443868 | 0.81 | GAA (0.51) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL5191624 | 0.81 | GAA (0.51) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL27693587 | 0.81 | GAA (0.70) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL4141601 | 0.81 | TSHR (0.54) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL5066246 | 0.81 | GAA (0.70) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL4141597 | 0.81 | TSHR (0.54) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL5060615 | 0.81 | GAA (0.70) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL24326690 | 0.80 | TRPM8 (0.59) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL1889631 | 0.80 | TRPM8 (0.59) | ITGB1ITGA5ITGB3ITGAVMEN1 | |
| SCHEMBL1889629 | 0.80 | TRPM8 (0.59) | ITGB1ITGA5ITGB3ITGAVMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BCAT2, BCAT1, FABP4 | ITGB1 4504/4885ITGA5 4159/4885ITGB3 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.