SCHEMBL31243849

SCHEMBL31243849

C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 2/20 0.52
▸ BACE1 P56817 1/20 0.52
▸ BACE2 Q9Y5Z0 1/20 0.52
▸ KISS1R Q969F8 4/20 0.52
▸ VIPR2 P41587 4/20 0.52
▸ VIPR1 P32241 2/20 0.52
▸ OPRL1 P41146 1/20 0.51
▸ OPRM1 P35372 3/20 0.51
▸ OPRD1 P41143 3/20 0.51
▸ OPRK1 P41145 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31243850 1.00 IL23R (0.52) IL23RBACE1BACE2KISS1RVIPR2
SCHEMBL31634763 1.00 IL23R (0.52) IL23RBACE1BACE2KISS1RVIPR2
SCHEMBL31243882 0.97 KISS1R (0.54) IL23RKISS1ROPRM1OPRD1OPRK1
SCHEMBL31243883 0.95 BACE1 (0.56) BACE1BACE2VIPR2OPRD1
SCHEMBL31243868 0.94 OPRD1 (0.54) BACE1BACE2KISS1ROPRM1OPRD1
SCHEMBL31243891 0.94 OPRD1 (0.54) BACE1BACE2KISS1ROPRM1OPRD1
SCHEMBL31243852 0.94 OPRD1 (0.54) BACE1BACE2KISS1ROPRM1OPRD1
SCHEMBL31243886 0.93 KISS1R (0.55) BACE1BACE2KISS1RVIPR2VIPR1
SCHEMBL31031570 0.92 KISS1R (0.60) IL23RKISS1ROPRL1OPRM1OPRD1
SCHEMBL29531061 0.92 OPRD1 (0.57) BACE1BACE2KISS1ROPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
CN-120202191-A Inhibitors of prostate specific membrane antigen and uses thereof 上海先通生物科技有限公司 2025-06-24 — — CN disclosed
CN-119072472-A FAP inhibitors 上海先通生物科技有限公司 2024-12-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP IL23R 1563/4885BACE1 254/4885BACE2 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback