Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958048 | 1.00 | MAPT (0.43) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL28914758 | 0.85 | ALDH1A1 (0.39) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL9691428 | 0.81 | KDM4E (0.38) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL28135777 | 0.80 | HCAR2 (0.36) | TSHRHCAR2KDM4EKMT2AALDH1A1 | |
| SCHEMBL23340379 | 0.78 | GABRP (0.45) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL27864934 | 0.77 | KDM4E (0.38) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL1082565 | 0.76 | HCAR2 (0.41) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL30575331 | 0.76 | KDM4E (0.41) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL13806634 | 0.76 | KDM4E (0.41) | MAPTTSHRHCAR2KDM4EKMT2A | |
| SCHEMBL22018876 | 0.76 | KDM4E (0.58) | MAPTTSHRHCAR2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316568-B | 2-Formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2024-11-08 | — | — | CN | disclosed |