Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851238 | 1.00 | HTR1A (0.43) | HTR1ASLC6A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22978732 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10MEN1MAPT | |
| SCHEMBL23851281 | 0.82 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10MEN1MAPT | |
| SCHEMBL28386256 | 0.81 | TRPV1 (0.42) | HTR1ASLC6A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14740641 | 0.80 | TP53 (0.55) | ALDH1A1MEN1MAPTKMT2AGAA | |
| SCHEMBL25314260 | 0.78 | CFTR (0.36) | ALDH1A1SLC6A4GAASMN1; SMN2TP53 | |
| SCHEMBL30930984 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10MEN1MAPT | |
| SCHEMBL28938505 | 0.78 | REN (0.39) | HTR1ASLC6A2ALDH1A1MEN1KMT2A | |
| SCHEMBL27508507 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10MEN1MAPT | |
| SCHEMBL1434922 | 0.75 | TRPV1 (0.54) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238793-A1 | FUSED TRIAZINONES FOR USE IN THE TREATMENT OF CANCER | RGENTA THERAPEUTICS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |