Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9122886 | 1.00 | CA1 (0.39) | CA1CA2PDE3AGRM2PIK3CD | |
| SCHEMBL19835515 | 0.92 | CA1 (0.39) | CA1CA2PDE3AGRM2PIK3CD | |
| SCHEMBL20231255 | 0.88 | CA1 (0.37) | CA1CA2PDE3APTGS2PARP1 | |
| SCHEMBL29790845 | 0.75 | PNMT (0.46) | PIK3CDPARP1PARP10KDM1AHTR2C | |
| SCHEMBL29989368 | 0.75 | MAPT (0.40) | CA1CA2PIK3CDKMT2AHTR6 | |
| SCHEMBL4523516 | 0.75 | PNMT (0.46) | PIK3CDPARP1PARP10KDM1AHTR2C | |
| SCHEMBL19023151 | 0.75 | DRD2 (0.43) | CA2 | |
| SCHEMBL8237889 | 0.75 | PIK3CD (0.36) | PIK3CDPARP1PARP10NOTUMRAB9A | |
| SCHEMBL9119279 | 0.75 | PNMT (0.46) | PIK3CDHTR6 | |
| SCHEMBL9125380 | 0.75 | HTR2A (0.48) | PIK3CDPARP1PARP10KDM1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713320-A2 | BCAT2 INHIBITORS | Agios Pharmaceuticals, Inc. (US) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024238820-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |