Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.61 |
| ▸ | TUBB | P07437 | 1/20 | 0.61 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.61 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.61 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.61 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30427425 | 1.00 | ALDH1A1 (0.73) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| Hydrochloric Acid SCHEMBL5065615 | 0.98 | ALDH1A1 (0.71) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL11146505 | 0.89 | KMT2A (0.65) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL155160 | 0.85 | MAPT (0.62) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL310457 | 0.85 | ALDH1A1 (1.00) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL27540714 | 0.84 | USP2 (0.63) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL7151804 | 0.83 | MEN1 (0.73) | ALDH1A1MAPTHPGDKMT2ANPC1 | |
| SCHEMBL30217617 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL761126 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAL3MBTL1HTTUSP2 | |
| SCHEMBL436586 | 0.83 | HTT (0.76) | ALDH1A1LMNAL3MBTL1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | claimed |
| CN-119039488-A | Auxiliary agent with compatibility and nucleation performance, preparation method and application | 合肥工业大学 | 2024-11-29 | — | — | CN | claimed |
| CN-113045504-B | Dacoti preparation method of nylon | 上海天慈国际药业有限公司 | 2024-09-17 | — | — | CN | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | claimed |
| CN-113045504-A | Preparation method of dacomitinib | 上海天慈国际药业有限公司 | 2021-06-29 | — | — | CN | claimed |
| US-20260144743-A1 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-05-28 | — | — | US | disclosed |
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| EP-3856178-B1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-11 | — | — | EP | disclosed |
| EP-4699655-A2 | COMPOUNDS | TMEM16A LIMITED (GB) | 2026-02-25 | — | — | EP | disclosed |
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2026-01-22 | — | — | US | disclosed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4150046-A | ORGANIC PIGMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125400-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, CSNK2A1, CSNK2A2 | ALDH1A1 3930/4885LMNA 2666/4885L3MBTL1 2459/4885 |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | ALDH1A1 295/4885LMNA 2696/4885L3MBTL1 1585/4885 |
| US-20260144743-A1 | COMPOUNDS | CACNA1E, TMEM109, CACNA1C | ALDH1A1 1592/4885LMNA 665/4885L3MBTL1 1483/4885 |
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | ALDH1A1 587/4885LMNA 1988/4885L3MBTL1 1163/4885 |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | ATG7, GOT1, ULK1 | ALDH1A1 601/4885LMNA 2223/4885L3MBTL1 930/4885 |
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, NR1H4, CNR1 | ALDH1A1 807/4885LMNA 3897/4885L3MBTL1 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.