Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CFB | P00751 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381126 | 1.00 | ACHE (0.45) | ACHEBACE1CNR2CFBDRD2 | |
| SCHEMBL25380096 | 0.91 | DRD2 (0.45) | ACHEBACE1CNR2DRD2TLR2 | |
| SCHEMBL25379938 | 0.87 | ACHE (0.45) | ACHEBACE1CNR2DRD2SIGMAR1 | |
| SCHEMBL25378584 | 0.82 | DRD2 (0.49) | CNR2DRD2SIGMAR1 | |
| SCHEMBL31252147 | 0.82 | DRD2 (0.49) | CNR2DRD2SIGMAR1 | |
| SCHEMBL7694998 | 0.78 | CYP3A4 (0.52) | DRD2 | |
| SCHEMBL322073 | 0.74 | RIPK1 (0.52) | USP30 | |
| SCHEMBL321319 | 0.74 | RIPK1 (0.52) | USP30 | |
| SCHEMBL24619422 | 0.73 | TDP1 (0.49) | ACHEBACE1CNR2DRD2 | |
| SCHEMBL24619420 | 0.73 | TDP1 (0.49) | ACHEBACE1CNR2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843616-A | Benzamide compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-10-25 | — | — | CN | disclosed |