Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | DRD1 | P21728 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | DRD5 | P21918 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378584 | 1.00 | DRD2 (0.49) | DRD2DRD3HTR1ADRD1DRD4 | |
| SCHEMBL14619656 | 0.83 | DRD2 (0.60) | DRD2DRD3SIGMAR1 | |
| SCHEMBL31252151 | 0.82 | ACHE (0.45) | DRD2CNR2SIGMAR1 | |
| SCHEMBL25381126 | 0.82 | ACHE (0.45) | DRD2CNR2SIGMAR1 | |
| SCHEMBL5510931 | 0.80 | DRD2 (0.60) | DRD2 | |
| SCHEMBL34474944 | 0.77 | CPT2 (0.44) | DRD2HTR1A | |
| SCHEMBL2556685 | 0.76 | PDE4B (0.56) | — | |
| SCHEMBL12501782 | 0.74 | DRD2 (0.65) | DRD2DRD3HTR1ADRD4SIGMAR1 | |
| SCHEMBL6848549 | 0.74 | CCR2 (0.50) | DRD2SIGMAR1 | |
| SCHEMBL9542849 | 0.74 | ROCK2 (0.49) | DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843616-A | Benzamide compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-10-25 | — | — | CN | disclosed |