Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2232470 | 1.00 | BRD4 (0.31) | BRD4CREBBPNPC1LMNATP53 | |
| Hydrochloric Acid SCHEMBL3684075 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL31255982 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL8459220 | 0.89 | TOP1 (0.32) | KIF11 | |
| Hydrochloric Acid SCHEMBL31255987 | 0.88 | KIF11 (0.37) | KIF11 | |
| Hydrochloric Acid SCHEMBL3687203 | 0.87 | SYK (0.33) | — | |
| Hydrochloric Acid SCHEMBL217395 | 0.85 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29556837 | 0.85 | PDCD1 (0.31) | — | |
| SCHEMBL27337668 | 0.79 | BRD4 (0.33) | BRD4CREBBPNPC1LMNATP53 | |
| Hydrochloric Acid SCHEMBL3693250 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852509-A | Catalyst composition for olefin polymerization, polymerization method and application thereof | 中化学科学技术研究有限公司 | 2024-10-29 | — | — | CN | disclosed |