Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL217395 | 0.90 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL29556837 | 0.90 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL31255985 | 0.87 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2232470 | 0.87 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8459220 | 0.86 | TOP1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3688170 | 0.82 | PBRM1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL31255982 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31255987 | 0.80 | KIF11 (0.37) | — | |
| Hydrochloric Acid SCHEMBL3684075 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3683368 | 0.78 | CA12 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| EP-2064248-B1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | disclosed |