SCHEMBL31257065

CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@H](C(=O)O)[C@@H](C)O

nearest known ligand 0.42

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MAGI3	Q5TCQ9	1/20	0.42

▸	ERBB2	P04626	1/20	0.41

▸	GRPR	P30550	3/20	0.41

▸	BACE1	P56817	11/20	0.40

▸	CTSD	P07339	1/20	0.40

▸	BACE2	Q9Y5Z0	1/20	0.38

▸	GLP1R	P43220	1/20	0.37

▸	SCTR	P47872	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257073	0.93	MAGI3 (0.44)	MAGI3ERBB2GRPRBACE1CTSD
SCHEMBL29805325	0.89	BACE1 (0.44)	MAGI3ERBB2BACE1CTSDBACE2
SCHEMBL31257050	0.88	BACE1 (0.42)	ERBB2BACE1CTSDBACE2GLP1R
SCHEMBL31256975	0.87	BACE1 (0.42)	GRPRBACE1CTSDBACE2GLP1R
SCHEMBL31257083	0.86	BACE1 (0.43)	MAGI3ERBB2GRPRBACE1CTSD
SCHEMBL31257072	0.86	MAGI3 (0.48)	MAGI3BACE1GLP1R
SCHEMBL29530913	0.86	MME (0.40)	MAGI3
SCHEMBL31256972	0.84	BACE1 (0.48)	BACE1CTSDBACE2
SCHEMBL29771459	0.83	BACE1 (0.41)	MAGI3BACE1GLP1R
SCHEMBL10533746	0.83	BACE1 (0.45)	GRPRBACE1CTSDBACE2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed