SCHEMBL31257004

SCHEMBL31257004

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 15/20 0.62
▸ OPRM1 P35372 7/20 0.58
▸ OPRK1 P41145 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29692598 0.96 OPRD1 (0.57) OPRD1OPRM1OPRK1
SCHEMBL7586040 0.89 OPRD1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL7586047 0.89 OPRD1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL29375823 0.89 IL1RN (0.55) OPRD1OPRM1OPRK1
SCHEMBL29366088 0.87 OPRD1 (0.52) OPRD1OPRM1OPRK1
SCHEMBL29794033 0.87 OPRD1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL30898603 0.86 OPRD1 (0.68) OPRD1OPRM1OPRK1
SCHEMBL15670400 0.86 LTA4H (0.57) OPRD1OPRM1OPRK1
SCHEMBL13878268 0.86 LTA4H (0.57) OPRD1OPRM1OPRK1
SCHEMBL22229862 0.86 LTA4H (0.57) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240352445-A1 HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES ABWIZ BIO, INC. 2024-10-24 — — US disclosed
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