SCHEMBL3125703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15946017	0.87	OPRM1 (0.45)	HTR6BRD4MAP2K4GHSRBRPF1
	SCHEMBL13355600	0.87	HTR6 (0.54)	HTR6BRD4PRMT6MAP2K4BRPF1
	SCHEMBL13355716	0.85	BRD4 (0.41)	HTR6BRD4PRMT6MAP2K4BRPF1
	SCHEMBL2150876	0.82	EPHX1 (0.46)	HTR6
	SCHEMBL3127769	0.81	HTR6 (0.53)	HTR6GHSROPRM1SLC2A1
	SCHEMBL4974327	0.79	HTR6 (0.57)	HTR6PRMT6MAP2K4BRPF1OPRM1
	SCHEMBL15054308	0.78	HTR6 (0.51)	HTR6BRD4MAP2K4BRPF1OPRM1
	SCHEMBL611010	0.77	HTR6 (0.42)	HTR6
	SCHEMBL2151236	0.76	CA1 (0.45)	—
	SCHEMBL3124999	0.76	MAP2K4 (0.44)	BRD4PRMT6MAP2K4BRPF1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.