SCHEMBL3127769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15946037	0.88	MEN1 (0.46)	HTR6MEN1KMT2AACLYADRB2
	SCHEMBL2151300	0.84	ACLY (0.44)	HTR6MEN1KMT2AACLYADRB2
	SCHEMBL3125703	0.81	HTR6 (0.57)	HTR6GHSRSLC2A1OPRM1
	SCHEMBL3137536	0.79	CA1 (0.43)	ACLY
	SCHEMBL28824395	0.79	HTR6 (0.61)	HTR6GHSR
	SCHEMBL3133186	0.78	ALDH1A1 (0.47)	MEN1KMT2AACLYALDH1A1
	SCHEMBL612943	0.77	SIGMAR1 (0.46)	NMT2NMT1OPRM1
	SCHEMBL612124	0.77	SIGMAR1 (0.46)	NMT2NMT1OPRM1
	SCHEMBL3133713	0.76	ACLY (0.41)	MEN1KMT2AACLYADRB3LMNA
	SCHEMBL2150885	0.76	HTR6 (0.45)	HTR6NMT2NMT1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.