SCHEMBL31257057

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	11/20	0.58

▸	OPRM1	P35372	10/20	0.58

▸	OPRK1	P41145	2/20	0.55

▸	BACE1	P56817	2/20	0.48

▸	BACE2	Q9Y5Z0	1/20	0.48

▸	APC	P25054	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31257019	0.91	OPRD1 (0.57)	OPRD1OPRM1OPRK1BACE1
SCHEMBL31256964	0.90	OPRD1 (0.58)	OPRD1OPRM1OPRK1
SCHEMBL31672201	0.90	OPRM1 (0.56)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31098023	0.90	OPRD1 (0.60)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL30477365	0.89	OPRD1 (0.58)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL29804763	0.89	OPRM1 (0.57)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31256991	0.88	OPRD1 (0.58)	OPRD1OPRM1OPRK1
SCHEMBL31257082	0.87	OPRD1 (0.56)	OPRD1OPRM1OPRK1
SCHEMBL30376274	0.87	OPRD1 (0.54)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31038686	0.87	OPRD1 (0.58)	OPRD1OPRM1OPRK1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20240352445-A1	HUMANIZATION, AFFINITY MATURATION, AND OPTIMIZATION METHODS FOR PROTEINS AND ANTIBODIES	ABWIZ BIO, INC.	2024-10-24	—	—	US	disclosed