SCHEMBL30477365

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	7/20	0.58

▸	OPRM1	P35372	4/20	0.58

▸	OPRK1	P41145	1/20	0.54

▸	BACE1	P56817	3/20	0.49

▸	BACE2	Q9Y5Z0	2/20	0.49

▸	GLP1R	P43220	2/20	0.47

▸	CCKAR	P32238	2/20	0.47

▸	CCKBR	P32239	2/20	0.47

▸	APC	P25054	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29804763	0.99	OPRM1 (0.57)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL30299009	0.96	OPRM1 (0.55)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL30376274	0.95	OPRD1 (0.54)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL29378801	0.93	BACE1 (0.54)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31098023	0.91	OPRD1 (0.60)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL29804647	0.90	BACE1 (0.51)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL29674783	0.90	OPRM1 (0.53)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31257057	0.89	OPRD1 (0.58)	OPRD1OPRM1OPRK1BACE1BACE2
SCHEMBL31256793	0.88	OPRM1 (0.55)	OPRD1OPRM1OPRK1GLP1R
SCHEMBL31672201	0.88	OPRM1 (0.56)	OPRD1OPRM1OPRK1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111320683-B	Tilappa peptide analogue	成都奥达生物科技有限公司	2023-06-27	—	—	CN	claimed
CN-111320683-B	Tilappa peptide analogue	成都奥达生物科技有限公司	2023-06-27	—	—	CN	disclosed