SCHEMBL29804763

SCHEMBL29804763

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)[C@@H](C)CC)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 4/20 0.57
▸ OPRD1 P41143 4/20 0.57
▸ OPRK1 P41145 1/20 0.54
▸ BACE1 P56817 4/20 0.49
▸ BACE2 Q9Y5Z0 2/20 0.49
▸ GLP1R P43220 2/20 0.48
▸ KISS1R Q969F8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30477365 0.99 OPRD1 (0.58) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL30299009 0.97 OPRM1 (0.55) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL30376274 0.96 OPRD1 (0.54) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29378801 0.94 BACE1 (0.54) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31098023 0.91 OPRD1 (0.60) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29804647 0.90 BACE1 (0.51) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29674783 0.89 OPRM1 (0.53) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31038686 0.89 OPRD1 (0.58) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL30407947 0.89 OPRM1 (0.55) OPRM1OPRD1OPRK1GLP1R
SCHEMBL31257057 0.89 OPRD1 (0.58) OPRM1OPRD1OPRK1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF NOVO NORDISK AS (DK) 2024-06-13 — — US claimed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 — — US claimed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 — — CN claimed
EP-4126921-A2 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 — — EP claimed
CN-115335395-A QD administration of GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2022-11-11 — — CN claimed
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-07-21 — — US claimed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 — — US disclosed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 — — CN disclosed
EP-4126921-A2 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 — — EP disclosed
EP-4126920-A2 GIF RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 — — EP disclosed
CN-115335395-A QD administration of GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2022-11-11 — — CN disclosed
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR OPRM1 290/4885OPRD1 272/4885OPRK1 257/4885
US-20220227830-A1 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR OPRM1 339/4885OPRD1 253/4885OPRK1 327/4885
US-20240190938-A1 GIP DERIVATIVES AND USES THEREOF GIPR, GLP1R, GPR119 OPRM1 861/4885OPRD1 1176/4885OPRK1 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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