Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258122 | 1.00 | MTNR1A (0.56) | MTNR1ATP53LMNAPOLBMAPT | |
| Hydrochloric Acid SCHEMBL31258028 | 0.99 | MTNR1A (0.55) | MTNR1ATP53LMNAPOLBMAPT | |
| SCHEMBL31258218 | 0.86 | MTNR1A (0.48) | MTNR1ATP53LMNAPOLBMAPT | |
| SCHEMBL16303447 | 0.78 | MTNR1A (0.58) | MTNR1ATP53LMNAPOLBMAPT | |
| SCHEMBL10225793 | 0.78 | DRD2 (0.50) | MTNR1ACYP19A1 | |
| SCHEMBL24239411 | 0.78 | MAOB (0.51) | — | |
| SCHEMBL26970908 | 0.78 | MAOB (0.51) | — | |
| SCHEMBL29052749 | 0.78 | MAOB (0.51) | — | |
| SCHEMBL17888019 | 0.78 | MTNR1A (0.64) | MTNR1ATP53LMNAPOLBMAPT | |
| SCHEMBL9082928 | 0.77 | MTNR1A (0.57) | MTNR1ATP53LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698529-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220173-A1 | BLOOD BRAIN BARRIER PENETRATING SELECTIVE INHIBITORS OF ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2024-10-24 | — | — | WO | disclosed |