SCHEMBL31258157

SCHEMBL31258157

CCO[Si](CCC=N)(OCC)OC(C)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.34
SIGMAR1 Q99720 5/20 0.34
MAOA P21397 4/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
TRPA1 O75762 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC18A2 Q05940 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP3A4 P08684 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAOB P27338 3/20 0.32
NISCH Q9Y2I1 3/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028386 0.84 SIGMAR1 (0.40) TAAR1SIGMAR1MAOASLC6A2SLC6A4
SCHEMBL614550 0.79 TAAR1 (0.39) TAAR1SIGMAR1MAOASLC6A2SLC6A4
SCHEMBL1519047 0.76 SIGMAR1 (0.35) TAAR1SIGMAR1MEN1KMT2ASLC18A2
SCHEMBL31028355 0.76 MEN1 (0.40) TAAR1SIGMAR1MEN1KMT2ACYP3A4
SCHEMBL28854442 0.75 TSHR (0.38) CYP2D6CYP3A4ALDH1A1TSHR
SCHEMBL28233865 0.74 CHRNB2 (0.39) TAAR1SIGMAR1MAOASLC6A2SLC6A4
SCHEMBL2526803 0.71 SMN1; SMN2 (0.33) SIGMAR1MEN1KMT2ACYP2D6TSHR
SCHEMBL2520769 0.71 SMN1; SMN2 (0.33) SIGMAR1KMT2ACYP2D6
SCHEMBL3206897 0.71
SCHEMBL15816499 0.69 SIGMAR1 (0.33) SIGMAR1SLC6A2SLC6A4SLC6A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039342-B Solid polymerization inhibitor for acrylic acid and esters thereof, preparation method and application 安庆精益精化工有限公司 2025-02-14 CN disclosed
CN-119039342-A Solid polymerization inhibitor for acrylic acid and esters thereof, preparation method and application 安庆精益精化工有限公司 2024-11-29 CN disclosed