Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259885 | 0.83 | ALDH1A1 (0.49) | TNFALDH1A1GAACYP2C19KMT2A | |
| SCHEMBL8883742 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAACYP2C19MEN1KMT2A | |
| SCHEMBL8883750 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAACYP2C19MEN1KMT2A | |
| SCHEMBL6260167 | 0.81 | TNF (0.53) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL31259790 | 0.79 | TNF (0.51) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL2167750 | 0.79 | ALDH1A1 (0.64) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL15930057 | 0.79 | ALDH1A1 (0.64) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL6255431 | 0.79 | TNF (0.53) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL31259808 | 0.78 | TNF (0.50) | TNFALDH1A1GAAATMMEN1 | |
| SCHEMBL7436698 | 0.77 | L3MBTL1 (0.57) | TNFALDH1A1GAAATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739668-A1 | 1,3-ISOINDOLINEDIONE DERIVATIVES AND HETEROAROMATIC ANALOGUES FOR STIMULATING ENDOTHELIAL CELL-PERICYTE INTERACTION | Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) (NL) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025014359-A1 | 1,3-ISOINDOLINEDIONE DERIVATIVES AND HETEROAROMATIC ANALOGUES FOR STIMULATING ENDOTHELIAL CELL-PERICYTE INTERACTION | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) | 2025-01-16 | — | — | WO | disclosed |