Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.31 |
| ▸ | HLCS | P50747 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264316 | 1.00 | NLRP3 (0.34) | NLRP3PDCD4HLCS | |
| SCHEMBL1895638 | 0.81 | PDCD4 (0.43) | NLRP3PDCD4 | |
| SCHEMBL8985124 | 0.81 | PDCD4 (0.43) | NLRP3PDCD4 | |
| SCHEMBL12673923 | 0.81 | PDCD4 (0.43) | NLRP3PDCD4 | |
| SCHEMBL9995097 | 0.80 | PAOX (0.36) | NLRP3PDCD4 | |
| SCHEMBL3505080 | 0.79 | PDCD4 (0.40) | NLRP3PDCD4 | |
| SCHEMBL9993662 | 0.78 | PDCD4 (0.31) | PDCD4 | |
| SCHEMBL9991171 | 0.77 | PDCD4 (0.37) | PDCD4 | |
| SCHEMBL9993726 | 0.77 | PDCD4 (0.38) | NLRP3PDCD4 | |
| SCHEMBL2672216 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400530-A1 | METHODS FOR PREPARING BUTENOLIDES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2024-12-05 | — | — | US | disclosed |
| CN-119060001-A | Process for preparing butenolide | 香港科技大学 | 2024-12-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400530-A1 | METHODS FOR PREPARING BUTENOLIDES | ME3, ME1, ME2 | NLRP3 3072/4885PDCD4 1617/4885HLCS 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.