SCHEMBL312645

SCHEMBL312645

O=C(O)c1ccc(OCCCCOc2ccccc2)cc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN11 Q06124 3/20 0.57
PKM P14618 1/20 0.56
ALDH1A1 P00352 2/20 0.56
KCNA3 P22001 1/20 0.55
POLB P06746 1/20 0.51
PLA2G4B P0C869 1/20 0.49
KMT2A Q03164 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC2 Q92769 1/20 0.49
PARP10 Q53GL7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29706508 1.00 PTPN11 (0.57) PTPN11PKMALDH1A1KCNA3POLB
SCHEMBL11459971 0.97 PKM (0.56) PTPN11PKMALDH1A1KCNA3POLB
SCHEMBL312644 0.95 PKM (0.62) PTPN11PKMALDH1A1KCNA3POLB
SCHEMBL29706606 0.95 PKM (0.62) PTPN11PKMALDH1A1KCNA3POLB
SCHEMBL31186568 0.91 PTPN11 (0.57) PTPN11ALDH1A1POLBPLA2G4B
SCHEMBL29712519 0.87 ALDH1A1 (0.58) PTPN11PKMALDH1A1POLB
SCHEMBL9303988 0.87 MCL1 (0.57) PTPN11PKMALDH1A1KCNA3PLA2G4B
SCHEMBL8053343 0.87 PPARD (0.57) PTPN11PKMALDH1A1KCNA3
SCHEMBL8062685 0.85 PPARD (0.56) PTPN11PKMALDH1A1
SCHEMBL8064850 0.85 PPARD (0.56) PTPN11PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000026037-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO claimed
JP-6321859-A None JP disclosed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-3758947-B1 HEAT SENSITIVE RECORDING MATERIAL AND COLOR DEVELOPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2025-05-14 EP disclosed
US-12151497-B2 Heat sensitive recording material with non-phenolic color developers SOLENIS TECHNOLOGIES, L.P. (US) 2024-11-26 US disclosed
US-11512048-B2 Heat sensitive recording material, and color developer SOLENIS TECHNOLOGIES, L.P. (US) 2022-11-29 US disclosed
CN-112601668-B Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2022-07-29 CN disclosed
CN-114667279-A Heat-sensitive recording material containing non-phenol color developer 索理思科技开曼公司 2022-06-24 CN disclosed
CN-112601668-A Thermosensitive recording material and color-developing agent 索理思科技开曼公司 2021-04-02 CN disclosed
US-20210060994-A1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS BASF SE (DE) 2021-03-04 US disclosed
WO-2000026037-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
WO-2000012513-A1 NOVEL PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed
EP-0928794-A1 Crystalline flouran compounds and their use in recording materials Ciba SC Holding AG (CH) 1999-07-14 EP disclosed
US-5622909-A DEVELOPER LAYER COMPRISING LEUCO DYE, PHTHALIC ACID DERIVATIVE; STORAGE STABILITY RICOH COMPANY, LTD. (JP) 1997-04-22 US disclosed
EP-0612628-B1 Thermosensitive recording material using phthalic acid derivatives RICOH KK (JP) 1996-07-10 EP disclosed
US-5482912-A DEVELOPERS, THERMAL PRINTING, INTERMEDIATE LAYER OF THERMOPLASTIC HOLLOW SPHERES RICOH COMPANY, LTD. (JP) 1996-01-09 US disclosed
US-5447900-A Fluoran leuco dye and developer RICOH COMPANY, LTD. (JP) 1995-09-05 US disclosed
JP-H06321859-A PRODUCTION OF PHTHALIC ACID COMPOUND CONTAINING ETHER GROUP RICOH CO LTD 1994-11-22 JP disclosed
EP-0612628-A1 Thermosensitive recording material using phthalic acid derivatives Ricoh Company, Ltd (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512048-B2 Heat sensitive recording material, and color developer SCN1A, NCS1, SCN5A PTPN11 4728/4885PKM 4155/4885ALDH1A1 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.