Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.84 |
| ▸ | HPGD | P15428 | 4/20 | 0.84 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CLK2 | P49760 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10767255 | 0.99 | ALDH1A1 (0.84) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL29388501 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL29895425 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL34610 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL133835 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL34609 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL9226104 | 0.92 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL8912235 | 0.91 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL30034879 | 0.91 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 | |
| Lomefloxacin SCHEMBL42052 | 0.91 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093381-B2 | Method of synthesis of fluoroquinolones | BIOCODEX (FR) | 2012-01-10 | — | — | US | disclosed |
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | BIOCODEX (FR) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054643-A1 | NOVEL METHOD OF SYNTHESIS OF FLUOROQUINOLONES | NQO2, Q6ZSR9, QARS1 | ALDH1A1 3146/4885KDM4E 2435/4885HSD17B10 1768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.